ruby - hamming

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# Hamming
Calculate the Hamming difference between two DNA strands.
A mutation is simply a mistake that occurs during the creation or
copying of a nucleic acid, in particular DNA. Because nucleic acids are
vital to cellular functions, mutations tend to cause a ripple effect
throughout the cell. Although mutations are technically mistakes, a very
rare mutation may equip the cell with a beneficial attribute. In fact,
the macro effects of evolution are attributable by the accumulated
result of beneficial microscopic mutations over many generations.
The simplest and most common type of nucleic acid mutation is a point
mutation, which replaces one base with another at a single nucleotide.
By counting the number of differences between two homologous DNA strands
taken from different genomes with a common ancestor, we get a measure of
the minimum number of point mutations that could have occurred on the
evolutionary path between the two strands.
This is called the 'Hamming distance'.
It is found by comparing two DNA strands and counting how many of the
nucleotides are different from their equivalent in the other string.
GAGCCTACTAACGGGAT
CATCGTAATGACGGCCT
^ ^ ^ ^ ^ ^^
The Hamming distance between these two DNA strands is 7.
# Implementation notes
The Hamming distance is only defined for sequences of equal length. This means
that based on the definition, each language could deal with getting sequences
of equal length differently.
* * * *
For installation and learning resources, refer to the
[exercism help page](http://exercism.io/languages/ruby).
For running the tests provided, you will need the Minitest gem. Open a
terminal window and run the following command to install minitest:
gem install minitest
If you would like color output, you can `require 'minitest/pride'` in
the test file, or note the alternative instruction, below, for running
the test file.
Run the tests from the exercise directory using the following command:
ruby hamming_test.rb
To include color from the command line:
ruby -r minitest/pride hamming_test.rb
## Source
The Calculating Point Mutations problem at Rosalind [http://rosalind.info/problems/hamm/](http://rosalind.info/problems/hamm/)
## Submitting Incomplete Solutions
It's possible to submit an incomplete solution so you can see how others have completed the exercise.

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# Running Tests
In order to complete this exercise, and all of the subsequent exercises, you
will need to pass multiple tests.
## Understanding Test Results
After you have created and saved `hamming.rb`, run the test suite. You should
see output like the following:
# Running:
SSSSSSESSSSSSSSS
Finished in 0.002593s, 6170.4588 runs/s, 0.0000 assertions/s.
1) Error:
HammingTest#test_identical_strands:
NameError: uninitialized constant HammingTest::Hamming
Did you mean? HammingTest
../hamming/hamming_test.rb:9:in `test_identical_strands'
16 runs, 0 assertions, 0 failures, 1 errors, 15 skips
You have skipped tests. Run with --verbose for details.
The letters `SSSSSSESSSSSSSSS` show that there are sixteen tests altogether,
that one of them has an error (`E`), and that the rest of them are skipped (all
the `S` letters).
The tests are run in randomized order, which will cause the letters to display
in random order as well.
The goal is to have all passing tests, which will show in two places:
1. `SSSSSSESSSSSSSSS` will become a series dots: `................`,
2. The line at the bottom will read `16 runs, 16 assertions, 0 failures, 0
errors, 0 skips`.
## Passing Tests
Write enough code to change the Error to Failure, and finally to Passing.
Open `hamming_test.rb`, and find the word "skip". All but the first test start
with "skip", which tells Minitest to ignore the test. This is so that you don't
have to deal with all the failures at once.
To activate the next test, delete the "skip", or comment it out, and run the
test suite again.
## Wash, Rinse, Repeat
Delete one "skip" at a time, and make each test pass before you move to the
next one.

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class Hamming
def self.compute(a, b)
if a.length != b.length
raise ArgumentError
end
distance = 0
0.upto(a.length - 1) do |i|
if a[i] != b[i]
distance += 1
end
end
distance
end
end

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require 'minitest/autorun'
require_relative 'hamming'
# Common test data version: 2.1.0 b5d154b
class HammingTest < Minitest::Test
def test_empty_strands
# skip
assert_equal 0, Hamming.compute('', '')
end
def test_identical_strands
# skip
assert_equal 0, Hamming.compute('A', 'A')
end
def test_long_identical_strands
# skip
assert_equal 0, Hamming.compute('GGACTGA', 'GGACTGA')
end
def test_complete_distance_in_single_nucleotide_strands
# skip
assert_equal 1, Hamming.compute('A', 'G')
end
def test_complete_distance_in_small_strands
# skip
assert_equal 2, Hamming.compute('AG', 'CT')
end
def test_small_distance_in_small_strands
# skip
assert_equal 1, Hamming.compute('AT', 'CT')
end
def test_small_distance
# skip
assert_equal 1, Hamming.compute('GGACG', 'GGTCG')
end
def test_small_distance_in_long_strands
# skip
assert_equal 2, Hamming.compute('ACCAGGG', 'ACTATGG')
end
def test_non_unique_character_in_first_strand
# skip
assert_equal 1, Hamming.compute('AAG', 'AAA')
end
def test_non_unique_character_in_second_strand
# skip
assert_equal 1, Hamming.compute('AAA', 'AAG')
end
def test_same_nucleotides_in_different_positions
# skip
assert_equal 2, Hamming.compute('TAG', 'GAT')
end
def test_large_distance
# skip
assert_equal 4, Hamming.compute('GATACA', 'GCATAA')
end
def test_large_distance_in_off_by_one_strand
# skip
assert_equal 9, Hamming.compute('GGACGGATTCTG', 'AGGACGGATTCT')
end
def test_disallow_first_strand_longer
# skip
assert_raises(ArgumentError) do
Hamming.compute('AATG', 'AAA')
end
end
def test_disallow_second_strand_longer
# skip
assert_raises(ArgumentError) do
Hamming.compute('ATA', 'AGTG')
end
end
end